Does Cranberry Juice Help Treat UTIs?
Considering cranberry juice for UTI prevention? Learn about its potential benefits and limitations based on scientific evidence.
Table of contents
Key Takeaways
- Cranberry Juice is a dietary supplement containing proanthocyanidins, a powerful compound obtained from cranberries known to treat urinary tract infections (UTIs).
- Because it prohibits certain bacteria from sticking to the urinary tract wall increases the acidity of urine and reduces the overgrowth of harmful bacteria and accumulation of bacteria in the urinary tract system.
- While several studies have linked the consumption of cranberry products to lower UTI risks, more research-based evidence is required to shed more light on how cranberry extract works to treat UTIs.
What is UTI?
Urinary tract infection commonly known by the acronym UTI is a bacterial infection that affects parts of the urinary system including the kidneys, bladder, ureters, and urethra. However, most UTI infections involve the lower urinary tract - the urethra and the bladder.
UTI is known to cause some level of discomfort and is characterized by symptoms like strong urge to urinate, frequent urination, passing a small amount of urine, blood spots in the urine, strong-smelling urine, and pelvic or abdominal pain. Research shows that women compared to men, are at a higher risk of developing these UTI symptoms.
UTIs occur when bacteria find their way to the urinary tract via the urethra and then spread to the bladder and other areas of the urinary system. The urinary system is generally responsible for keeping out bacteria.
However, the defenses sometimes may fail causing the bacteria to clutch and grow on the urinary tract wall, eventually leading to a complete infection in the urinary tract system. Other causes of UTIs include chronic diseases known to compromise the immune system such as HIV and diabetes.
Kidney stones and urinary catheters have also been found to cause obstruction to the urinary tract, leading to UTIs. The use of contraceptive diaphragm or spermicide-coated condoms has also been linked to UTIs.
How Cranberry Juice Works for UTIs?
Besides antibiotics, most people also opt for natural remedies to treat and prevent UTIs. Among the most popular natural alternatives for treating and preventing UTIs is cranberry juice UTI.
Cranberry juice contains a compound called proanthocyanidins (PACs) which according to various studies can play a pivotal role in preventing UTIs thanks to its antibacterial activity against bacteria’s susceptible strains and antibiotic resistance. One study found that PACs can aid in the prevention of UTIs by stopping bacteria’s adherence to the urinary tract.
Diet cranberry juice has also been found to possess other potent compounds like flavonoids and phenolic acids with the ability to prevent and treat various UTIs. Phenolic acid, for instance, works by increasing urine acidity which in turn reduces the overgrowth of harmful bacteria.
Cranberry juice benefits are generally immense. The compounds in cranberry extract have demonstrated their ability to prevent bacteria from sticking to the urinary tract wall, reduce inflammation, modulate gut bacteria, and reduce the number of bacteria in the gastrointestinal tract and bladder likely to cause UTIs.
The Evidence: Does Cranberry Juice Really Help Prevent UTI?
While the supplementation of unsweetened cranberry juice UTI has been linked to a number of benefits, there are those who want to know if the benefits claims have scientific evidence. This is because while there is a group of researchers who find the available cranberry juice UTI evidence to be enough to support the extract’s benefit claims, others still argue that the health benefits claims are just a myth as the scientific evidence is still not convincing.
Now, the only way to definitively disprove the myth of preventing UTIs is to analyze research supporting the cranberry extract's health benefits claims on preventing and treating UTI symptoms. Various researchers have pointed out the varied mechanisms through which the cranberry extract works to address UTI symptoms as discussed below:
One mechanism by which cranberry juice may help prevent UTIs is by increasing urine acidity. Increasing urine acidity has been linked to a reduction in bacteria overgrowth due to the presence of proanthocyanidins (PACs) in it.
Excess bacteria in the urinary tract system, especially the bladder have been shown to cause various undesirable infections which can cause some level of discomfort if not addressed in good time.
A research study published in Research Microbiology found that acidification of urine can cause major antimicrobial activity impairment and neutralization.
Another cranberry juice may help prevent UTIs by inhibiting bacteria from adhering to the urinary tract walls, thus keeping bacteria out of the urinary tract system and ensuring that it does not spread into the bladder and other parts of the urinary system to cause infection.
Research published in Drug Journal notes that supplementation of cranberry juice cannot treat UTIs but has demonstrated anti-adhesion ability by preventing the adhesion of P-fimbriated and type 1 uropathogen, thus impairing infection establishment.
However, there is still no substantial evidence that cranberry juice can actually be beneficial in managing UTI symptoms because some research and clinical tests have failed to give convincing evidence. Again, some researchers still argue that until the right dosage intake is determined through human clinical tests, the efficacy claims remain unfounded.
Studies have shown that UTI occurs mainly in women because of male and female anatomical differences. Women have shorter urethra compared to men which makes it easy for the bacteria to travel into the bladder.
One study has noted that 50 percent of women compared to 12 percent of men, are likely to develop UTI in a lifetime. Another research study shows that up to 30 percent of young women have had recurrent UTIs, which has had a negative impact on their quality of life.
Studies show that females may benefit more from taking cranberry juice, especially when it comes to preventing UTI recurrence. A study conducted involving 1, 498 healthy women exposed to cranberry supplements showed a significant reduction in UTI recurrence by 26%, thus demonstrating cranberry extract’s protective effect against UTIs.
It is evident that taking cranberry supplements is beneficial for both female and male seeking to enhance the potential benefits of cranberry juice in preventing UTIs.
How to Use Cranberry Juice for UTIs?
The question most people continue to ask is how much cranberry juice should you drink for a urinary tract infection? The truth is that the dosage information available online is varied and therefore, contradicting.
For instance, we have one study recommended taking 240-300 ml of cranberry extract per day while another study recommended the intake of 200-500 mg per day to treat UTIs.
Most cranberry supplements available on the market today are in the form of capsules, tablets, and juice with dosage included. However, you will notice that the dosage intake varies from one brand to the other.
This may leave you wondering which brand is giving the right dosage not just for efficiency but for safety purposes too.
Most cranberry supplements available on the market today are in the form of capsules, tablets, and juice with dosage included. However, you will notice that the dosage intake varies from one brand to the other.
This may leave you wondering which brand is giving the right dosage not just for efficiency but for safety purposes too.
If you're considering using cranberry juice capsules, or tablets to treat a UTI, we strongly recommend consulting your physician. They can advise you on the appropriate dosage and timing for your specific needs.
Also, choosing the cranberry supplement can be a challenge, especially if there are a number of them on the market from different brands.
They are also in different forms so they may vary in terms of absorption and efficiency. So, before you settle for a given form ensure that you have researched and compared its pros and cons.
Also, to increase your chances of choosing high-quality or the best cranberry juice UTI product, you need to consider the following:
- Customer reviews: Researching customer reviews is important because it will give you more insight into different cranberry supplements and improve your chances of selecting the right product for your UTI issues.
- Ingredients: Checking on the ingredients used in the supplement formulation including their scientific backing and proven clinical tests lets you know if the product contains ingredients that work to deliver results.
- Dosage: Dosage consideration when selecting cranberry supplements is important because the right dosage ensures that you are taking the right amount that will ensure effectiveness and safety.
- Brand: Selecting cranberry supplements from a reputable brand guarantees your product authenticity and best quality.
Potential Side Effects and Considerations
Cranberry juice if taken in moderation should deliver results without harming your health. However, several side effects like nausea and vomiting have been reported. Stomach upset and kidney stones have also been identified as potential side effects associated with taking cranberry in high doses.
A study published in Planta Medical Journal notes that though there isn’t conclusive evidence, cranberry has been associated with kidney stone-related health risks if taken in excess.
Because of the factors associated with cranberry intake, it is important to consult with your healthcare provider to help you determine the right dosage and if it is safe to use it along with your current medication.
Also, if you are wondering if you can take cranberry pills with antibiotics for UTI, the answer is yes. One study has recommended the use of cranberry juice consumption along with oral antibiotics to prevent the recurrence of UTIs.
Other Natural Remedies for UTIs
- Drinking lots of water: Research published in JAMA International Medicine notes that taking plenty of water every day can offer a protective effect against UTI recurrence.
- Frequent bladder emptying: Delaying bladder emptying or not urinating frequently can promote bacteria growth and its accumulation in the urinary tract, thus leading to UTI recurrence, especially in women.
- Wiping front to back after using the toilet: Women are encouraged to wipe front to back after using the toilet to prevent the transfer of bacteria from the anus to the urethra.
- Keeping off irritating substances: Avoiding the use of scented toilet paper and bubble baths can also protect your urinary tract from infections.
When to See a Doctor
If you start experiencing pelvic pain, frequent urge to urinate, pain during urination, or other uncomfortable UTI symptoms, you should schedule an appointment with the doctor.
Treating these symptoms in time prevents you from developing chronic health conditions including kidney and liver problems.
Conclusion
Research studies have shown that cranberry products such as cranberry supplements and cranberry juice can help reduce or prevent UTIs and their recurrence.
However, scientific evidence of these health claims is still limited, meaning that more studies on cranberry extract’s efficiency are required.
So, if you are experiencing frequent UTIs and wish to prevent their recurrence, we recommend working with your doctor so that together you can come up with a treatment plan which may include the use of supplements and other lifestyle changes.
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References
- Cranberries for Preventing Urinary Tract Infections https://pubmed.ncbi.nlm.nih.gov/37068952/
- Cranberry and Urinary Tract Infections https://pumed.ncbi.nlm.nih.gov/19441868/
- Cranberry Polyphenols and Prevention Against Urinary Tract Infections: Relevant Consideration https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436188/
- Effects of Cranberry Juice on Pharmacokinetics of Bet-Lactam Antibiotics Following Oral Administration https://www.pubmed.ncbi.nlm.gov/19398645/
- Safety of Cranberry: Evaluation of Evidence of Kidney Stone Formation and Botanical Drug-Interactions https://pubmed.nbci.nlm.nih.gov/34015833/
- Effects of Increased Daily Water Intake in Premenopausal Women with Recurrent Urinary Tract Infections https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584323/
- Complicated Urinary Tract Infections https://www.ncbi.nlm.nih.gov/books/NBK436013/
- Cranberry Polyphenols and Prevention Against Urinary Tract Infections: Relevant Considerations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436188/
- Impact of pH on Bacterial Growth and Activity of Recent Fluoroquinolones in Pooled Urine https://pubmed.ncbi.nlm.nih.gov/21288486/
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